Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    A new method of prenatal alcohol classification accounting for dose, pattern, and timing of exposure: Improving our ability to examine fetal effects from low to moderate exposure

    202067_13615_A_new_method.....J_Epidemiol_Community_Health-2009-O_Leary-jech.2009.091785.pdf (170.3Kb)
    Access Status
    Open access
    Authors
    O'Leary, C.
    Bower, C.
    Zubrick, Stephen
    Geelhoed, E.
    Kurinczuk, J.
    Nassar, N.
    Date
    2010
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    O'Leary, C. and Bower, C. and Zubrick, S. and Geelhoed, E. and Kurinczuk, J. and Nassar, N. 2010. A new method of prenatal alcohol classification accounting for dose, pattern, and timing of exposure: Improving our ability to examine fetal effects from low to moderate alcohol. Journal of Epidemiology and Community Health. 64 (11): pp. 956-962.
    Source Title
    Journal of Epidemiology and Community Health
    DOI
    10.1136/jech.2009.091785
    ISSN
    0143-005X
    School
    Centre for Developmental Health (Curtin Research Centre)
    URI
    http://hdl.handle.net/20.500.11937/9124
    Collection
    • Curtin Research Publications
    Abstract

    Background: When examining the association between prenatal alcohol exposure and fetal effects, the timing and intensity of exposure have been ignored in epidemiological studies. The effect of using dose, pattern and timing of consumption (“composite” method) was investigated in this study, to examine the association between prenatal alcohol exposure and fetal effects. Methods: The composite method resulted in six categories of exposure (abstinent, low, moderate, binge <weekly, binge 1–2×/week and heavy). The odds of language delay and child behaviour problems were calculated for the composite method and then compared with an analysis using averaged estimates of <1 and 1+ drinks per day and with stratification by quantity ignoring dose per occasion. Data used for the analyses were from a 10% random sample of non-Indigenous women delivering a live infant in Western Australia (1995–1997). Participants from the 1995-1996 cohort were invited to participate in an 8-year longitudinal survey (78% response rate n=2224; 85% were followed-up at 2 years, 73% at 5 years and 61% at 8 years). Results: The effect of moderate and binge levels of exposure was only evident with the composite method; anxiety/depression following first-trimester moderate exposure (OR 2.24, 95% CI 1.16 to 4.34), and following late pregnancy moderate (aggressive behaviour OR 1.93, 95% CI 0.91 to 4.09) and binge (language delay OR 3.00, 95% CI 0.90 to 9.93) exposures. Results for heavy levels of exposure were similar with each method. The estimates for late pregnancy were imprecise due to small numbers. Conclusion: The composite method of classification more closely reflects real-life drinking patterns and better discriminates maternal drinking than the other methods, particularly low, moderate and binge levels.

    Related items

    Showing items related by title, author, creator and subject.

    • Weight Suppression in Bulimia Nervosa: Relationship with Cognitive Behavioral Therapy Outcome
      Dawkins, Hayley; Watson, Hunna; Egan, Sarah; Kane, Robert (2013)
      Objective: In light of prior inconsistent findings, this study revisits the relationship between weight suppression and treatment outcome in bulimia nervosa. Aside from differences in methodology, we propose that moderator ...
    • Prenatal alcohol exposure and educational achievement in children aged 8-9 years
      O'Leary, Colleen; Taylor, Catherine; Zubrick, Stephen; Kurinczuk, J.; Bower, C. (2013)
      Objective: This study examines the relationships between the dose, pattern, and timing of prenatal alcohol exposure and achievement in reading, writing, spelling, and numeracy in children aged 8 to 9 years. Methods: Data ...
    • Gross Motor Deficits in Children Prenatally Exposed to Alcohol: A Meta-analysis
      Lucas, B.; Latimer, J.; Pinto, R.; Ferreira, M.; Doney, Robyn; Lau, M.; Jones, T.; Dries, D.; Elliott, E. (2014)
      Background and Objectives: Gross motor (GM) deficits are often reported in children with prenatal alcohol exposure (PAE), but their prevalence and the domains affected are not clear. The objective of this review was to ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.