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dc.contributor.authorNyadanu, Sylvester
dc.contributor.authorDunne, Jennifer
dc.contributor.authorTessema, Gizachew
dc.contributor.authorMullins, Ben
dc.contributor.authorKumi-Boateng, B.
dc.contributor.authorLee Bell, M.
dc.contributor.authorAdema, Bereket Duko
dc.contributor.authorPereira, Gavin
dc.date.accessioned2023-11-16T08:32:22Z
dc.date.available2023-11-16T08:32:22Z
dc.date.issued2022
dc.identifier.citationNyadanu, S.D. and Dunne, J. and Tessema, G.A. and Mullins, B. and Kumi-Boateng, B. and Lee Bell, M. and Duko, B. et al. 2022. Prenatal exposure to ambient air pollution and adverse birth outcomes: An umbrella review of 36 systematic reviews and meta-analyses. Environmental Pollution. 306: ARTN 119465.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/93794
dc.identifier.doi10.1016/j.envpol.2022.119465
dc.description.abstract

Multiple systematic reviews and meta-analyses linked prenatal exposure to ambient air pollutants to adverse birth outcomes with mixed findings, including results indicating positive, negative, and null associations across the pregnancy periods. The objective of this study was to systematically summarise systematic reviews and meta-analyses on air pollutants and birth outcomes to assess the overall epidemiological evidence. Systematic reviews with/without meta-analyses on the association between air pollutants (NO2, CO, O3, SO2, PM2.5, and PM10) and birth outcomes (preterm birth; stillbirth; spontaneous abortion; birth weight; low birth weight, LBW; small-for-gestational-age) up to March 30, 2022 were included. We searched PubMed, CINAHL, Scopus, Medline, Embase, and the Web of Science Core Collection, systematic reviews repositories, grey literature databases, internet search engines, and references of included studies. The consistency in the directions of the effect estimates was classified as more consistent positive or negative, less consistent positive or negative, unclear, and consistently null. Next, the confidence in the direction was rated as either convincing, probable, limited-suggestive, or limited non-conclusive evidence. Final synthesis included 36 systematic reviews (21 with and 15 without meta-analyses) that contained 295 distinct primary studies. PM2.5 showed more consistent positive associations than other pollutants. The positive exposure-outcome associations based on the entire pregnancy period were more consistent than trimester-specific exposure averages. For whole pregnancy exposure, a more consistent positive association was found for PM2.5 and birth weight reductions, particulate matter and spontaneous abortion, and SO2 and LBW. Other exposure-outcome associations mostly showed less consistent positive associations and few unclear directions of associations. Almost all associations showed probable evidence. The available evidence indicates plausible causal effects of criteria air pollutants on birth outcomes. To strengthen the evidence, more high-quality studies are required, particularly from understudied settings, such as low-and-middle-income countries. However, the current evidence may warrant the adoption of the precautionary principle.

dc.languageEnglish
dc.publisherELSEVIER SCI LTD
dc.relation.sponsoredbyhttp://purl.org/au-research/grants/nhmrc/1195716
dc.relation.sponsoredbyhttp://purl.org/au-research/grants/nhmrc/1099655
dc.relation.sponsoredbyhttp://purl.org/au-research/grants/nhmrc/1173991
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectEnvironmental Sciences
dc.subjectEnvironmental Sciences & Ecology
dc.subjectAir pollution
dc.subjectBirth outcomes
dc.subjectBirth weight
dc.subjectStillbirth
dc.subjectPreterm birth
dc.subjectUmbrella review
dc.subjectFINE PARTICULATE MATTER
dc.subjectPREGNANCY OUTCOMES
dc.subjectPRETERM BIRTH
dc.subjectWEIGHT
dc.subjectASSOCIATION
dc.subjectHEALTH
dc.subjectPM2.5
dc.subjectMETAANALYSIS
dc.subjectIMPACT
dc.subjectSCIENCE
dc.subjectAir pollution
dc.subjectBirth outcomes
dc.subjectBirth weight
dc.subjectPreterm birth
dc.subjectStillbirth
dc.subjectUmbrella review
dc.subjectAbortion, Spontaneous
dc.subjectAir Pollutants
dc.subjectAir Pollution
dc.subjectEnvironmental Exposure
dc.subjectFemale
dc.subjectHumans
dc.subjectInfant, Newborn
dc.subjectMaternal Exposure
dc.subjectParticulate Matter
dc.subjectPregnancy
dc.subjectPremature Birth
dc.subjectPrenatal Exposure Delayed Effects
dc.subjectHumans
dc.subjectAbortion, Spontaneous
dc.subjectPremature Birth
dc.subjectPrenatal Exposure Delayed Effects
dc.subjectAir Pollutants
dc.subjectAir Pollution
dc.subjectEnvironmental Exposure
dc.subjectMaternal Exposure
dc.subjectPregnancy
dc.subjectInfant, Newborn
dc.subjectFemale
dc.subjectParticulate Matter
dc.titlePrenatal exposure to ambient air pollution and adverse birth outcomes: An umbrella review of 36 systematic reviews and meta-analyses
dc.typeJournal Article
dcterms.source.volume306
dcterms.source.issn0269-7491
dcterms.source.titleEnvironmental Pollution
dc.date.updated2023-11-16T08:32:20Z
curtin.departmentCurtin School of Population Health
curtin.departmentOffice of the Pro Vice Chancellor Health Sciences
curtin.accessStatusOpen access
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidPereira, Gavin [0000-0003-3740-8117]
curtin.contributor.orcidTessema, Gizachew [0000-0002-4784-8151]
curtin.contributor.orcidMullins, Ben [0000-0002-6722-1073]
curtin.contributor.orcidAdema, Bereket Duko [0000-0002-4419-0016]
curtin.contributor.orcidNyadanu, Sylvester [0000-0002-6233-0262]
curtin.contributor.orcidDunne, Jennifer [0000-0002-1001-732X]
curtin.contributor.researcheridPereira, Gavin [D-7136-2014]
curtin.contributor.researcheridTessema, Gizachew [J-9235-2018]
curtin.identifier.article-numberARTN 119465
dcterms.source.eissn1873-6424
curtin.contributor.scopusauthoridPereira, Gavin [35091486200]
curtin.contributor.scopusauthoridMullins, Ben [7003349055]
curtin.contributor.scopusauthoridAdema, Bereket Duko [56845644100]
curtin.contributor.scopusauthoridNyadanu, Sylvester [57204853128]
curtin.contributor.scopusauthoridDunne, Jennifer [57250660000]
curtin.repositoryagreementV3


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