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Risk factors for borderline personality disorder in treatment seeking patients with a substance use disorder: An international multicenter study

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Open access
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2015
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Journal Article

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Wapp, M. and Van De Glind, G. and Van Emmerik-Van Oortmerssen, K. and Dom, G. and Verspreet, S. and Carpentier, P. and Ramos-Quiroga, J. et al. 2015. Risk factors for borderline personality disorder in treatment seeking patients with a substance use disorder: An international multicenter study. European Addiction Research. 21 (4): pp. 188-194.
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European Addiction Research
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National Drug Research Institute (NDRI)
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This is the peer-reviewed but unedited manuscript version of the following article: European Addiction Research 2015; 21 (4): 188-194 (DOI: 10.1159/000371724). The final, published version is available at http://www.karger.com/10.1159/000371724.

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Abstract

Borderline personality disorder (BPD) and substance use disorders (SUDs) often co-occur, partly because they share risk factors. In this international multicenter study, risk factors for BPD were examined for SUD patients. In total, 1,205 patients were comprehensively examined by standardized interviews and questionnaires on psychiatric diagnosis and risk factors, and it was found that 1,033 (85.7%) had SUDs without BPD (SUD) and 172 (14.3%) had SUD with BPD (SUD + BPD). SUD + BPD patients were significantly younger, more often females and more often diagnosed with comorbid adult attention deficit/hyperactivity disorder. SUD + BPD patients did not differ from SUD patients on most risk factors typical for SUD such as maternal use of drugs during pregnancy or parents having any SUD. However, SUD + BPD patients did have a higher risk of having experienced emotional and physical abuse, neglect, or family violence in childhood compared to SUD patients, suggesting that child abuse and family violence are BPD-specific risk factors in patients with SUDs.