Clearing Things Up: Examining the Past, Present and Future of Airway Clearance in Adults with Cystic Fibrosis

Abstract

This PhD body of research aimed to provide further evidence to determine, in adults with CF: (i) the current evidence for effects of airway clearance techniques (ACTs) used; (ii) the responsiveness of novel outcome measures to evaluate the effects of ACTs; (iii) the effects of a new ACT, the MetaNeb®; and (iv) individuals’ lived experiences before and after Trikafta® initiation, specifically regarding their respiratory-related symptoms, airway clearance routines and capacity to participate in physical activity.