RNA-Scoop: Interactive visualization of transcripts in single-cell transcriptomes

Stephenson, M.; Nip, K.M.; Hafezqorani, S.; Gagalova, Kristina; Yang, C.; Warren, R.L.; Birol, I.

doi:10.1093/nargab/lqab105

Access Status

In process

Authors

Stephenson, M.

Nip, K.M.

Hafezqorani, S.

Gagalova, Kristina

Yang, C.

Warren, R.L.

Birol, I.

Date

2021

Type

Journal Article

Metadata

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Citation

Stephenson, M. and Nip, K.M. and Hafezqorani, S. and Gagalova, K.K. and Yang, C. and Warren, R.L. and Birol, I. 2021. RNA-Scoop: Interactive visualization of transcripts in single-cell transcriptomes. NAR Genomics and Bioinformatics. 3 (4): pp. lqab105-.

Source Title

NAR Genomics and Bioinformatics

DOI

10.1093/nargab/lqab105

ISSN

2631-9268

Faculty

Faculty of Science and Engineering

School

School of Molecular and Life Sciences (MLS)

URI

http://hdl.handle.net/20.500.11937/96870

Collection

Curtin Research Publications

Abstract

Recent advances in single-cell RNA sequencing technologies have made detection of transcripts in single cells possible. The level of resolution provided by these technologies can be used to study changes in transcript usage across cell populations and help investigate new biology. Here, we introduce RNA-Scoop, an interactive cell cluster and transcriptome visualization tool to analyze transcript usage across cell categories and clusters. The tool allows users to examine differential transcript expression across clusters and investigate how usage of specific transcript expression mechanisms varies across cell groups.