Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine
Access Status
Fulltext not available
Authors
Carter, Damien
Rohl, Andrew
Shtukenberg, A.
Bian, S.
Hu, C.
Baylon, L.
Kahr, B.
Mineki, H.
Abe, K.
Kawasaki, T.
Soai, K.
Date
2012Type
Journal Article
Metadata
Show full item recordCitation
Carter, Damien and Rohl, Andrew and Shtukenberg, Alexander and Bian, Shudan and Hu, Chunhua and Baylon, Lisa and Kahr, Bart and Mineki, Hiroko and Abe, Koichiro and Kawasaki, Tsuneomi and Soai, Kenso. 2012. Prediction of Soai Reaction Enantioselectivity Induced by Crystals of N-(2-Thienylcarbonyl)glycine. Crystal Growth and Design 12 (4) : pp. 2138-2145.
Source Title
Crystal Growth and Design
Additional URLs
ISSN
Collection
Abstract
The enantioselectivity of the autocatalytic alkylation of 2-tert-butylpyrimidyl-5-carbaldehyde, initiated by chiral crystals of N-(2-thienylcarbonyl)glycine, is predicted computationally. The results are in accord with the correlation of the stereochemical outcome of the reaction and the absolute structure of the crystals determined by the anomalous dispersion of X-rays and circular dichroism spectroscopy.