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    Therapeutic antibodies: Discovery, design and deployment

    Access Status
    Fulltext not available
    Authors
    Ramsland, Paul
    Hutchinson, A.
    Carter, P.
    Date
    2015
    Type
    Journal Article
    
    Metadata
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    Citation
    Ramsland, P. and Hutchinson, A. and Carter, P. 2015. Therapeutic antibodies: Discovery, design and deployment. Molecular Immunology. 67 (2, Part A): pp. 1-3.
    Source Title
    Molecular Immunology
    DOI
    10.1016/j.molimm.2015.05.004
    ISSN
    0161-5890
    School
    School of Biomedical Sciences
    URI
    http://hdl.handle.net/20.500.11937/11166
    Collection
    • Curtin Research Publications
    Abstract

    Therapeutic antibodies have come of age with major progress being made in cancer, autoimmunity and chronic inflammation, as well as a wide range of other human diseases. Antibody engineering is further driving development of novel antibody formats and genetically modified cell-based therapies that harness the power of the immune system to progress cures in otherwise intractable human diseases. Nevertheless, there are still significant challenges ahead for basic and applied research relating to therapeutic antibodies. This special issue of the journal provides reviews and opinions that relate to the discovery, design and deployment of antibodies as therapeutics.

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