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dc.contributor.authorSlater, Helen
dc.contributor.authorArendt-Nielsen, Lars
dc.contributor.authorWright, Tony
dc.contributor.authorGraven-Nielsen, Thomas
dc.identifier.citationSlater, Helen and Arendt-Nielsen, Lars and Wright, Antony and Graven-Nielsen, Thomas. 2005. Sensory and motor effects of experimental muscle pain in patients with lateral epicondylalgia and controls with delayed onset muscle soreness. Pain. 114 (1-2): 118-130.

This study compares the effect of experimental muscle pain on deep tissue sensitivity and force attenuation in the wrist extensors of patients with lateral epicondylalgia (n=20), and healthy controls (n=20) with experimentally induced sensori-motor characteristics simulating lateral epicondylalgia. Delayed onset muscle soreness (DOMS) in wrist extensors of healthy controls was induced by eccentric exercise in one arm 24 h prior to injection (Day 0). Saline-induced pain intensity (visual analogue scale, VAS), distribution, and quality were assessed quantitatively in both arms for both groups. Pressure pain thresholds (PPT) were assessed at three different sites in the wrist extensors. Maximal grip force and wrist extension force were recorded. In response to saline-induced pain in the extensor carpi radialis brevis, regardless of arm, the patient group demonstrated a significantly quicker pain onset (P<0.01), mapped larger pain areas and more referred pain areas, compared to healthy controls (P<0.03). Pain persisted significantly longer in the sore arm of the patient group, compared with all other arms (P<0.02). Patients demonstrated significant bilateral hyperalgesia at extensor carpi radialis brevis during and post saline-induced pain compared to pre-injection and healthy controls (P<0.04). The sore arm in patients and the DOMS arms in healthy subjects showed significantly reduced maximal force (P<0.0001), at all Day 1 times compared with the control arms. In patients, the bilateral increase in deep tissue sensitivity and enlarged referred pain areas during saline-induced pain might suggest involvement of central sensitisation.

dc.subjectCentral sensitisation
dc.subjectPeripheral sensitisation
dc.subjectLateral epicondylalgia
dc.subjectExperimental muscle pain
dc.subjectDelayed onset muscle soreness (DOMS)
dc.subjectReferred pain
dc.titleSensory and motor effects of experimental muscle pain in patients with lateral epicondylalgia and controls with delayed onset muscle soreness
dc.typeJournal Article
curtin.departmentCenter for Sensory-Motor Interaction, Aalborg University, Denmark
curtin.accessStatusFulltext not available
curtin.facultySchool of Physiotherapy
curtin.facultyDivision of Health Sciences

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