Soleus Muscle as a Surrogate for Health Status in Human Heart Failure
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This is a non-final version of an article published in final form in Green, D. and Panizzolo, F. and Lloyd, D. and Rubenson, J. and Maiorana, A. 2016. Soleus Muscle as a Surrogate for Health Status in Human Heart Failure. Exercise and Sport Sciences Reviews. 44 (1): pp. 45-50.
We propose the hypothesis that soleus muscle function may provide a surrogate measure of functional capacity in patients with heart failure. We summarize literature pertaining to skeletal muscle as a locus of fatigue and present our recent findings, utilising in vivo imaging in combination with biomechanical experimentation and modelling, to reveal novel structure-function relationships in CHF skeletal muscle and gait.
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