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dc.contributor.authorVallance, J.
dc.contributor.authorBoyle, Terry
dc.contributor.authorCourneya, K.
dc.contributor.authorLynch, B.
dc.date.accessioned2017-01-30T11:26:16Z
dc.date.available2017-01-30T11:26:16Z
dc.date.created2016-04-28T19:30:18Z
dc.date.issued2014
dc.identifier.citationVallance, J. and Boyle, T. and Courneya, K. and Lynch, B. 2014. Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors. Cancer. 120 (18): pp. 2919-2926.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/11682
dc.identifier.doi10.1002/cncr.28779
dc.description.abstract

BACKGROUND: The primary purpose of this study was to determine associations of accelerometer-assessed moderate- to vigorousintensity physical activity (MVPA) and sedentary time with health-related quality of life (HRQoL) and physical function and well-being in colon cancer survivors. METHODS: Colon cancer survivors (N=178) from Alberta, Canada (n=92) and Western Australia (n=86) completed a mailed survey that assessed HRQoL (Functional Assessment of Cancer Therapy-Colorectal), physical function and wellbeing (Trial Outcome Index-Colorectal), and relevant covariates. MVPA and sedentary time were assessed using the Actigraph GT3X1 accelerometer (60-second epochs) via a 7-day monitoring protocol. Average daily MVPA and sedentary time was corrected for wear time and then examined as quartiles. RESULTS: Adjusting for relevant demographic, behavioral, and clinical covariates, a significant difference in HRQoL scores emerged between quartile 1 (Q1) and Q4 (Mdiff=11.5, P=.038). For physical function and wellbeing, a significant difference emerged between Q1 and Q4 (Mdiff=9.1, P=.009). For fatigue, a significant difference emerged between Q1 and Q4 (Mdiff=7.1, P=.05). Significant differences were also observed for between Q1 and Q3 (Mdiff=2.4, P=.041), and Q1 and Q4 (Mdiff=3.5, P=.002) for colorectal cancer-specific symptoms. There were no statistically significant associations of sedentary time with HRQoL, physical function and well-being, fatigue, or colorectal cancer-specific symptoms. CONCLUSIONS: Objectively measured MVPA, but not sedentary time, was associated with better HRQoL, physical function and well-being, and colorectal cancer- specific symptoms in colon cancer survivors. For MVPA, differences met or exceeded contemporary cutpoints for determining clinically important differences.

dc.publisherJohn Wiley & Sons, Inc.
dc.titleAssociations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors
dc.typeJournal Article
dcterms.source.volume120
dcterms.source.number18
dcterms.source.startPage2919
dcterms.source.endPage2926
dcterms.source.issn0008-543X
dcterms.source.titleCancer
curtin.departmentEpidemiology and Biostatistics
curtin.accessStatusOpen access via publisher


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