Tetrazoles: a new class of compound for crystallization modification

Abstract

Tetrazoles are a class of organic compound often used as carboxylic acid analogues. This analogous behaviour is shown to extend to crystallization modification, that is, tetrazoles are also able to influence crystal growth and morphology although in a different manner to their carboxylate counterparts. All the tetrazoles investigated thus far are shown to impact on barium sulfate and calcium carbonate crystallization to varying degrees. Thus, the tetrazoles represent a new class of crystal modifier.