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dc.contributor.authorPatton, Kirralee Anne
dc.contributor.supervisorDr Ashleigh Murch
dc.contributor.supervisorProf. John Wetherall
dc.contributor.supervisorDr Narelle Hadlow
dc.date.accessioned2017-01-30T09:46:31Z
dc.date.available2017-01-30T09:46:31Z
dc.date.created2014-02-07T06:24:09Z
dc.date.issued2013
dc.identifier.urihttp://hdl.handle.net/20.500.11937/134
dc.description.abstract

The effects of cell culture on X chromosome aneuploidy in young women with established fertility were investigated. Fluorescence in situ hybridisation was performed on paired samples of mitogen stimulated and uncultured lymphocytes using probes for the X and 9 chromosomes. All participants had <5% X aneuploidy in both preparations. X chromosome loss occurred more frequently than gain. These results provide important information when interpreting the low levels of X mosaicism seen in routine cytogenetic practice.

dc.languageen
dc.publisherCurtin University
dc.titleThe effect of cell culture on X chromosome mosaicism
dc.typeThesis
dcterms.educationLevelM.Sc.
curtin.departmentSchool of Biomedical Science
curtin.accessStatusOpen access


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