The effect of cell culture on X chromosome mosaicism
| dc.contributor.author | Patton, Kirralee Anne | |
| dc.contributor.supervisor | Dr Ashleigh Murch | |
| dc.contributor.supervisor | Prof. John Wetherall | |
| dc.contributor.supervisor | Dr Narelle Hadlow | |
| dc.date.accessioned | 2017-01-30T09:46:31Z | |
| dc.date.available | 2017-01-30T09:46:31Z | |
| dc.date.created | 2014-02-07T06:24:09Z | |
| dc.date.issued | 2013 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/134 | |
| dc.description.abstract |
The effects of cell culture on X chromosome aneuploidy in young women with established fertility were investigated. Fluorescence in situ hybridisation was performed on paired samples of mitogen stimulated and uncultured lymphocytes using probes for the X and 9 chromosomes. All participants had <5% X aneuploidy in both preparations. X chromosome loss occurred more frequently than gain. These results provide important information when interpreting the low levels of X mosaicism seen in routine cytogenetic practice. | |
| dc.language | en | |
| dc.publisher | Curtin University | |
| dc.title | The effect of cell culture on X chromosome mosaicism | |
| dc.type | Thesis | |
| dcterms.educationLevel | MSc | |
| curtin.department | School of Biomedical Science | |
| curtin.accessStatus | Open access |