Creating a protein ontology resource
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Protein Data Integration approaches at the moment considers data sources as data repositories, but not as applications; which in turn may embody complex interactions with other data sources. Current approaches do not provide methods both for generic mapping protein data representation, depicting interactions in data it describes and for interfacing existing data. The proposed Protein Ontology shows the value of hierarchy and relationships present in proteomics data. The creation of a Protein Ontology provides understanding of diverse types of data like:(1) Protein Entry Details(2) 3D Structural Representations of Proteins(3) Structural Folds and domains conserved in proteins(4) Functional Domains and Families created based on Physiological and Pathological Functions of Proteins, and(5) Various Constraints like Genetic Defects and Chemical Properties of Cell that affect Final Stable Molecular Structure of Protein.Protein Ontology describes the concepts of interest in protein complex mechanisms and proteomics process.
Copyright 2005 IEEE
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Sidhu, Amandeep; Dillon, Tharam S.; Hussain, Farookh Khadeer; Chang, Elizabeth (2006)Recent progress in proteomics, computational biology, and ontology development has presented an opportunity to investigate protein data sources from unique perspective that is, examining protein data sources through ...
Chang, Elizabeth; Sidhu, Amandeep; Dillon, Tharam S.; Sidhu, B. (2005)In this paper, we propose an approach to integrate protein information from various data sources by defining a Protein Ontology. Protein Ontology provides the technical and scientific infrastructure and knowledge to allow ...
Hussain, Farookh Khadeer; Sidhu, Amandeep; Dillon, Tharam S.; Chang, Elizabeth (2006)Biomedical Ontologies are huge. It is not possible for any one person to manage and engineer a complete ontology. They would need the help of Research Assistants and other people to develop and maintain the ontology. In ...