TNF haplotypes in a Southern African population resemble those seen in Caucasians and Asians
dc.contributor.author | Chew, C. | |
dc.contributor.author | Wadley, A. | |
dc.contributor.author | Lombard, Z. | |
dc.contributor.author | Kamerman, P. | |
dc.contributor.author | Price, Patricia | |
dc.date.accessioned | 2017-01-30T11:40:35Z | |
dc.date.available | 2017-01-30T11:40:35Z | |
dc.date.created | 2015-10-29T04:10:06Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Chew, C. and Wadley, A. and Lombard, Z. and Kamerman, P. and Price, P. 2013. TNF haplotypes in a Southern African population resemble those seen in Caucasians and Asians. Genes and Immunity. 14 (4): pp. 268-270. | |
dc.identifier.uri | http://hdl.handle.net/20.500.11937/13961 | |
dc.identifier.doi | 10.1038/gene.2013.8 | |
dc.description.abstract |
Haplotypes spanning the tumor necrosis factor (TNF) gene block in the central major histocompatibility complex were defined in a Southern African population using 31 single-nucleotide polymorphisms. Twenty haplotypes accounted for 91.8% of the cohort. The haplotypes matched those described previously in Caucasian and Asian populations, supporting the hypothesis that TNF block haplotypes are ancient and highly conserved. They are presented here as a tool for disease-association studies. © 2013 Macmillan Publishers Limited. | |
dc.title | TNF haplotypes in a Southern African population resemble those seen in Caucasians and Asians | |
dc.type | Journal Article | |
dcterms.source.volume | 14 | |
dcterms.source.number | 4 | |
dcterms.source.startPage | 268 | |
dcterms.source.endPage | 270 | |
dcterms.source.issn | 1466-4879 | |
dcterms.source.title | Genes and Immunity | |
curtin.department | School of Biomedical Sciences | |
curtin.accessStatus | Fulltext not available |
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