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dc.contributor.authorChew, C.
dc.contributor.authorWadley, A.
dc.contributor.authorLombard, Z.
dc.contributor.authorKamerman, P.
dc.contributor.authorPrice, Patricia
dc.date.accessioned2017-01-30T11:40:35Z
dc.date.available2017-01-30T11:40:35Z
dc.date.created2015-10-29T04:10:06Z
dc.date.issued2013
dc.identifier.citationChew, C. and Wadley, A. and Lombard, Z. and Kamerman, P. and Price, P. 2013. TNF haplotypes in a Southern African population resemble those seen in Caucasians and Asians. Genes and Immunity. 14 (4): pp. 268-270.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/13961
dc.identifier.doi10.1038/gene.2013.8
dc.description.abstract

Haplotypes spanning the tumor necrosis factor (TNF) gene block in the central major histocompatibility complex were defined in a Southern African population using 31 single-nucleotide polymorphisms. Twenty haplotypes accounted for 91.8% of the cohort. The haplotypes matched those described previously in Caucasian and Asian populations, supporting the hypothesis that TNF block haplotypes are ancient and highly conserved. They are presented here as a tool for disease-association studies. © 2013 Macmillan Publishers Limited.

dc.titleTNF haplotypes in a Southern African population resemble those seen in Caucasians and Asians
dc.typeJournal Article
dcterms.source.volume14
dcterms.source.number4
dcterms.source.startPage268
dcterms.source.endPage270
dcterms.source.issn1466-4879
dcterms.source.titleGenes and Immunity
curtin.departmentSchool of Biomedical Sciences
curtin.accessStatusFulltext not available


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