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    The role of b-type natriuretic peptide in heart failure management

    133434_Newton_the role of b-type.pdf (65.74Kb)
    Access Status
    Open access
    Authors
    Newton, Phillip
    Betihavas, Vasiliki
    Macdonald, P.
    Date
    2009
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Newton, Phillip and Betihavas, Vasiliki and Macdonald, Peter. 2009. The role of b-type natriuretic peptide in heart failure management. Australian Critical Care. 22 (3): pp. 117-123.
    Source Title
    Australian Critical Care
    DOI
    10.1016/j.aucc.2009.06.001
    ISSN
    1036-7314
    Faculty
    School of Nursing and Midwifery
    Faculty of Health Sciences
    Remarks

    The link to the journal’s home page is: http://www.australiancriticalcare.com/ Copyright © 2009 Elsevier B.V. All rights reserved

    URI
    http://hdl.handle.net/20.500.11937/14305
    Collection
    • Curtin Research Publications
    Abstract

    Summary. Heart failure is a complex clinical syndrome that manifests itself with signs and symptoms which are neither sensitive nor specific for the diagnosis of heart failure. Natriuretic peptides and in particular b-type natriuretic peptide (and nt-proBNP) are widely used in clinical practice around the world as a maker of heart failure. BNP is primarly released from the left ventricle in response to pressure and volume overload. The strongest evidence for the use of BNP is to rule in or rule out heart failure as cause of breathlessness in people who present to the emergency room. There is enthusiasm for use of BNP as a market of heart failure severity as well as a predictor of outcomes in people with heart failure and trials are ongoing. Nesiritide, a recombinant form of BNP is currently being tested as a possible treatment in people with acutely decompensated heart failure.

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