Endocrine and immune responses to resistance training in prostate cancer patients

Galvao, D; Nosaka, K; Taaffe, D; Peake, J; Spry, N; Suzuki, K; Yamaya, K; McGuigan, M; Kristjanson, Linda; Newton, R

doi:10.1038/sj.pcan.4500991

Access Status

Open access via publisher

Authors

Galvao, D

Nosaka, K

Taaffe, D

Peake, J

Spry, N

Suzuki, K

Yamaya, K

McGuigan, M

Kristjanson, Linda

Newton, R

Date

2008

Type

Journal Article

Metadata

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Citation

Galvao, D. and Nosaka, K. and Taaffe, D. and Peake, J. and Spry, Nigel and Suzuki, K. and Yamaya, K. and McGuigan, M. and Kristjanson, Linda and Newton, R. 2008. Endocrine and immune responses to resistance training in prostate cancer patients. Prostate Cancer and Prostatic Diseases. 11 (2): pp. 160-165.

Source Title

Prostate Cancer and Prostatic Diseases

DOI

10.1038/sj.pcan.4500991

ISSN

13657852

Faculty

School of Nursing and Midwifery

Faculty of Health Sciences

WA Centre for Cancer and Palliative Care (WACCPC)

Remarks

URI

http://hdl.handle.net/20.500.11937/16264

Collection

Curtin Research Publications

Abstract

This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-alpha and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.