A genetic study of Attention-Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder and Reading Disability: Aetiological overlaps and implications
MetadataShow full item record
Attention Deficit Hyperactivity Disorder (ADHD) commonly co-occurs with Oppositional Defiant Disorder, Conduct Disorder and Reading Disability. Twin studies are an important approach to understanding and modelling potential causes of such comorbidity. Univariate and bivariate genetic models were fitted to maternal report data from 2040 families of twins from the Australian Twin ADHD Project. All measures showed a heritability of over 0.8 and little role for the common family environment, except for the combined subtype of ADHD with a heritability of 0.69 and a common environment of 0.19. About one-third of the genetic variance in ADHD was shared with the other behaviours, the largest overlap being with Oppositional Defiant Disorder. Common environmental effects were shared between the combined ADHD subtype and the other measures. Some implications of these findings for home and school are discussed.
Showing items related by title, author, creator and subject.
Attention deficit/hyperactivity disorders with co-existing substance use disorder is characterized by early antisocial behaviour and poor cognitive skillsBihlar Muld, B.; Jokinen, J.; Bölte, Sven; Hirvikoski, T. (2013)Background: Attention Deficit/Hyperactivity Disorder (ADHD) is associated with an increased risk of co-existing substance abuse. The Swedish legislation on compulsory healthcare can be applied to persons with severe ...
Kinstenius, M.; Leifman, A.; van Emmerik-van Oortmerssen, K.; van de Glind, G.; Franck, J.; Moggi, F.; Ramos-Quiroga, J.; Levin, F.; Carpentier, P.; Skuttle, A.; Bu, E.; Kaye, S.; Demetrovics, Z.; Barta, C.; Auriecomb, M.; Fatséas, M.; Johnson, B.; Faraone, S.; Allsop, Steve; Carruthers, Susan; Schoevers, R.; Verspreet, S.; Dom, G.; Koeter, M.; van den Brink, W. (2017)Background: Childhood trauma exposure (CTE) is frequently reported by those with substance use disorders (SUDs). SUDs also frequently co-occur with attention deficit hyperactivity disorder (ADHD). Objective: To investigate ...
Dyck, M.; Piek, Jan (2014)Objective: ADHD is often comorbid with other disorders, but it is often assumed that academic, language, or motor c skills problems are secondary to ADHD rather than that attention problems are secondary to the other ...