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    Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months?

    202575_134190_Ross_River_Virus_infection_surveillance.pdf (354.0Kb)
    Access Status
    Open access
    Authors
    Selvey, Linda
    Donelly, J.
    Lindsay, M.
    Boddu, S.
    D'Abrera, V.
    Smith, D.
    Date
    2014
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Selvey, L. and Donelly, J. and Lindsay, M. and Boddu, S. and D'Abrera, V. and Smith, D. 2014. Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? Communicable Diseases Intelligence Quarterly Report. 38 (2): pp. E114-121.
    Source Title
    National Center for Biotechnology Information
    Additional URLs
    http://www.health.gov.au/internet/main/publishing.nsf/Content/cda-cdi3802-pdf-cnt.htm/$FILE/cdi3802c.pdf
    ISSN
    1060-8788
    School
    School of Public Health
    URI
    http://hdl.handle.net/20.500.11937/18485
    Collection
    • Curtin Research Publications
    Abstract

    An increase in off-season (June to September) Ross River virus (RRV) notifications from the greater Perth metropolitan area was observed from 2006 to 2009. We investigated the increase to determine whether it is likely to have reflected a true increase in off-season cases. A single positive RRV IgM test result is sufficient for RRV notification but where follow-up testing was performed, the positive pre- dictive value of an IgM test where IgG was nega- tive was very low in the off-season and also in the season when using the only commercially available test kit. The increase in off-season notifications was not associated with an increase in off-season test- ing. Some Perth laboratories use more stringent notification criteria than the nationally agreed RRV case definition, and the geographical distribution of samples tested varies between laboratories. Our findings make a strong case to change the nationally agreed case definition for RRV to not accept a single IgM positive test result as labora- tory definitive evidence where the IgG is negative. Our study also identified a range of challenges in interpreting changes in seasonal patterns and geo- graphical distribution of RRV. Any such observed changes should be investigated through further data analysis and/or mosquito trapping and test- ing in order to assess validity.

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