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Is Pulmonary non-Tuberculous Mycobacterial Disease Linked with a High Burden of Latent Cytomegalovirus?

dc.contributor.authorAmran, F.
dc.contributor.authorKim, K.
dc.contributor.authorLim, A.
dc.contributor.authorThomson, R.
dc.contributor.authorLee, S.
dc.contributor.authorWaterer, G.
dc.contributor.authorPrice, Patricia
dc.date.accessioned2017-01-30T12:09:13Z
dc.date.available2017-01-30T12:09:13Z
dc.date.created2016-03-16T19:30:17Z
dc.date.issued2016
dc.identifier.citationAmran, F. and Kim, K. and Lim, A. and Thomson, R. and Lee, S. and Waterer, G. and Price, P. 2016. Is Pulmonary non-Tuberculous Mycobacterial Disease Linked with a High Burden of Latent Cytomegalovirus? Journal of Clinical Immunology. 36 (2): pp. 113-116.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/18652
dc.identifier.doi10.1007/s10875-016-0233-1
dc.description.abstract

© 2016 Springer Science+Business Media New York. Cytomegalovirus (CMV) establishes lifelong infections with episodes of active replication. We hypothesized that recurrent CMV replication in older individuals may suppress protective immune responses to non-tuberculous mycobacteria (NTM) and so potentiate pulmonary disease. Accordingly, levels of antibodies to three CMV antigen preparations were higher in NTM patients than in age-matched controls. This did not reflect broad-spectrum B cell activation as total immunoglobulin levels were not equivalently increased.
dc.titleIs Pulmonary non-Tuberculous Mycobacterial Disease Linked with a High Burden of Latent Cytomegalovirus?
dc.typeJournal Article
dcterms.source.volume36
dcterms.source.startPage113
dcterms.source.endPage116
dcterms.source.issn0271-9142
dcterms.source.titleJournal of Clinical Immunology
curtin.departmentSchool of Biomedical Sciences
curtin.accessStatusFulltext not available


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