Pancreatic cancer: Current research and future directions
Abstract
© 2016 Elsevier B.V. Despite the survival rate advancements in different types of cancer in the last 40 years, the perspective for pancreatic cancer patients has seen no substantial changes. Indeed, the five year survival rate remains around 5%. Nevertheless, in the last decade we have witnessed an increased interest in pancreatic cancer biology and this has produced a substantial increment in our knowledge on pancreatic cancer progression. The big challenge is now to translate this knowledge in better outcomes for patients. The aim of this review is to describe the latest discoveries and advancements in pancreatic cancer research and to discuss future directions.
Citation
Falasca, M. and Kim, M. and Casari, I. 2016. Pancreatic cancer: Current research and future directions. Biochimica et Biophysica Acta - Reviews on Cancer. 1865 (2): pp. 123-132.
Source Title
Biochimica et Biophysica Acta - Reviews on Cancer
ISSN
School
School of Biomedical Sciences
Collection
Related items
Showing items related by title, author, creator and subject.
-
Schulte, A.; Pandeya, N.; Fawcett, J.; Fritschi, Lin; Klein, K.; Risch, H.; Webb, P.; Whiteman, D.; Neale, R. (2016)PURPOSE: Family history of pancreatic adenocarcinoma is an established risk factor for the disease. However, associations of pancreatic cancer with other familial cancers are less clear. We analyzed data from the Queensland ...
-
Casari, I.; Falasca, Marco (2015)Pancreatic cancer is without any doubt the malignancy with the poorest prognosis and the lowest survival rate. This highly aggressive disease is rarely diagnosed at an early stage and difficult to treat due to its resistance ...
-
Neale, R.; Clark, P.; Fawcett, J.; Fritschi, Lin; Nagler, B.; Risch, H.; Walters, R.; Crawford, W.; Webb, P.; Whiteman, D.; Buchanan, D. (2014)Pancreatic cancer is a leading cause of cancer-related deaths worldwide. Methylation of DNA may influence risk or be a marker of early disease. The aim of this study was to measure the association between methylation of ...