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dc.contributor.authorHerzog, G.
dc.contributor.authorEichelmann-Daly, P.
dc.contributor.authorArrigan, Damien
dc.date.accessioned2017-01-30T12:26:41Z
dc.date.available2017-01-30T12:26:41Z
dc.date.created2010-10-27T20:02:46Z
dc.date.issued2010
dc.identifier.citationHerzog, Gregoire and Eichelmann-Daly, Patrycja and Arrigan, Damien. 2010. Electrochemical behaviour of denatured haemoglobin at the liquid|liquid interface. Electrochemistry Communications. 12 (3): pp. 335-337.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/21677
dc.identifier.doi10.1016/j.elecom.2009.12.020
dc.description.abstract

We report here the influence of chemical denaturation of haemoglobin on its electrochemical behaviour at the polarised liquid|liquid interface. Denaturation with urea resulted in a modification of the haemoglobin electrochemical behaviour, with the disappearance of the forward transfer peak and a decrease of the reverse peak current. Although the reverse peak current increased linearly with the concentration of denatured haemoglobin in the aqueous phase, the slope of the current-concentration plot was three times lower than that for native haemoglobin over the 0.1-1 μM concentration range. These results indicate the sensitivity of electrochemistry at liquid|liquid interfaces to protein tertiary structure.

dc.publisherElsevier
dc.subjectLiquid|liquid interface
dc.subjectDenaturation
dc.subjectVoltammetry
dc.subjectHaemoglobin
dc.subjectProtein
dc.titleElectrochemical behaviour of denatured haemoglobin at the liquid|liquid interface
dc.typeJournal Article
dcterms.source.volume12
dcterms.source.startPage335
dcterms.source.endPage337
dcterms.source.issn13882481
dcterms.source.titleElectrochemistry Communications
curtin.note

The link to the journal’s home page is:http://www.elsevier.com/wps/find/journaldescription.cws_home/601449/description#description Copyright © 2010 Elsevier B.V. All rights reserved

curtin.departmentNanochemistry Research Institute (Research Institute)
curtin.accessStatusOpen access
curtin.facultyNanochemistry Research Institute (NRI)
curtin.facultyFaculty of Science and Engineering


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