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    Amino acids and diabetes: implications for endocrine, metabolic and immune function

    Access Status
    Fulltext not available
    Authors
    Newsholme, Philip
    Abdulkader, F.
    Rebelato, E.
    Romanatto, T.
    Pinheiro, C.
    Vitzel, K.
    Silva, E.
    Bazotte, R.
    Procopio, J.
    Curi, R.
    Gorjao, R.
    Pithon-Curi, T.
    Date
    2011
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Newsholme, P. and Abdulkader, F. and Rebelato, E. and Romanatto, T. and Pinheiro, C. and Vitzel, K. and Silva, E. et al. 2011. Amino acids and diabetes: implications for endocrine, metabolic and immune function. Frontiers in Bioscience. 16: pp. 315-339.
    Source Title
    Frontiers in Bioscience
    DOI
    10.2741/3690
    ISSN
    1093-9946
    URI
    http://hdl.handle.net/20.500.11937/21909
    Collection
    • Curtin Research Publications
    Abstract

    Aberrant alterations in glucose and lipid concentrations and their pathways of metabolism are a hallmark of diabetes. However, much less is known about alterations in concentrations of amino acids and their pathways of metabolism in diabetes. In this review we have attempted to highlight, integrate and discuss common alterations in amino acid metabolism in a wide variety of cells and tissues and relate these changes to alterations in endocrine, physiologic and immune function in diabetes.

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