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    What keeps a body moving? The brain-derived neurotrophic factor val66met polymorphism and intrinsic motivation to exercise in humans

    213219_213219.pdf (595.8Kb)
    Access Status
    Open access
    Authors
    Caldwell Hooper, A.
    Bryan, A.
    Hagger, Martin
    Date
    2014
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Caldwell Hooper, A. and Bryan, A. and Hagger, M. 2014. What keeps a body moving? The brain-derived neurotrophic factor val66met polymorphism and intrinsic motivation to exercise in humans. Journal of Behavioral Medicine. 37 (6): pp. 1180-1192.
    Source Title
    Journal of Behavioral Medicine
    DOI
    10.1007/s10865-014-9567-4
    ISSN
    01607715
    School
    School of Psychology and Speech Pathology
    URI
    http://hdl.handle.net/20.500.11937/22868
    Collection
    • Curtin Research Publications
    Abstract

    Individuals who are intrinsically motivated to exercise are more likely to do so consistently. In previous research, those with at least one copy of the methionine (met) allele in the brain-derived neurotrophic factor gene (BDNF; rs6265) had greater increases in positive mood and lower perceived exertion during exercise. This study examined whether genotype for BDNF is also related to intrinsic motivation, measured by self-report during a treadmill exercise session and a free-choice behavioral measure (continuing to exercise given the option to stop) among 89 regular exercisers (age M = 23.58, SD = 3.95). Those with at least one copy of the met allele reported greater increases in intrinsic motivation during exercise and were more likely to continue exercising when given the option to stop (55 vs. 33 %). Results suggest that underlying genetic factors may partially influence perceptions of inherent rewards associated with exercise and might inform the development of individually targeted interventions.

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