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dc.contributor.authorEllis, J.
dc.contributor.authorHerzog, G.
dc.contributor.authorGlynn, B.
dc.contributor.authorArrigan, Damien
dc.date.accessioned2017-01-30T12:47:53Z
dc.date.available2017-01-30T12:47:53Z
dc.date.created2011-11-18T01:21:25Z
dc.date.issued2011
dc.identifier.citationEllis, Jonathan and Herzog, Gregoire and Glynn, B and Arrigan, Damien. 2011. Electrochemical Characterization of Regularly-aligned Nanopore Array Membranes Filled with Electrolyte Solutions and their use for Detection of Nucleic Acid Hybridization. ECS Transactions. 35 (7): pp. 29-44.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/25329
dc.identifier.doi10.1149/1.3571974
dc.description.abstract

We report on the electrochemical characterization of regularlyaligned cylindrical nanopore arrays supported in silicon nitride membranes and preliminary results for the detection of nucleic acid hybridization on the nanopore walls. A range of nanopore arrays with diameters between 40 and 150 nm were examined. We tested the effect of pore diameter, number of pores, electrolyte concentration and surface chemistry on the conductance of the nanopore membranes. The pores were functionalized with singlestranded DNA and conductance measurements were performed before and after hybridization. In many cases, changes in current rectification were observed following hybridization, which is discussed as a strategy for nucleic acid hybridization and interactions.

dc.publisherThe Electrochemical Society
dc.titleElectrochemical Characterization of Regularly-aligned Nanopore Array Membranes Filled with Electrolyte Solutions and their use for Detection of Nucleic Acid Hybridization
dc.typeJournal Article
dcterms.source.volume35
dcterms.source.number7
dcterms.source.startPage29
dcterms.source.endPage44
dcterms.source.issn1938-5862
dcterms.source.titleECS Transactions
curtin.note

Copyright © The Electrochemical Society, Inc. 2011. All rights reserved. Except as provided under U.S. copyright law, this work may not be reproduced, resold, distributed, or modified without the express permission of The Electrochemical Society (ECS). The archival version of this work was published in ECS Transactions, 35 (7): pp. 29-44.

curtin.departmentNanochemistry Research Institute (Research Institute)
curtin.accessStatusOpen access


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