Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor ß (TR-ß) selective ligands
| dc.contributor.author | Raval, S. | |
| dc.contributor.author | Raval, P. | |
| dc.contributor.author | Bandyopadhyay, D. | |
| dc.contributor.author | Soni, K. | |
| dc.contributor.author | Yevale, D. | |
| dc.contributor.author | Jogiya, D. | |
| dc.contributor.author | Modi, H. | |
| dc.contributor.author | Joharapurkar, A. | |
| dc.contributor.author | Gandhi, Neha | |
| dc.contributor.author | Jain, M. | |
| dc.contributor.author | Patel, P. | |
| dc.date.accessioned | 2017-01-30T12:49:23Z | |
| dc.date.available | 2017-01-30T12:49:23Z | |
| dc.date.created | 2016-09-12T08:36:25Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Raval, S. and Raval, P. and Bandyopadhyay, D. and Soni, K. and Yevale, D. and Jogiya, D. and Modi, H. et al. 2008. Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor ß (TR-ß) selective ligands. Bioorganic & Medicinal Chemistry Letters. 18 (14): pp. 3919-3924. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/25636 | |
| dc.identifier.doi | 10.1016/j.bmcl.2008.06.038 | |
| dc.description.abstract |
Design and synthesis of a novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives are reported and their in vitro thyroid hormone receptor selectivity has been evaluated in the thyroid luciferase receptor assay. The 3-[3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)-phenylamino]-4-hydroxy- cyclobut-3-ene-1,2-dione 21 has shown selectivity towards thyroid hormone receptor ß. © 2008 Elsevier Ltd. All rights reserved. | |
| dc.publisher | Pergamon | |
| dc.title | Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor ß (TR-ß) selective ligands | |
| dc.type | Journal Article | |
| dcterms.source.volume | 18 | |
| dcterms.source.number | 14 | |
| dcterms.source.startPage | 3919 | |
| dcterms.source.endPage | 3924 | |
| dcterms.source.issn | 0960-894X | |
| dcterms.source.title | Bioorganic & Medicinal Chemistry Letters | |
| curtin.department | School of Biomedical Sciences | |
| curtin.accessStatus | Fulltext not available |
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