Ontology-based Knowledge Representation for Protein Data
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Copyright 2005 IEEE
Reprinted from: 2005 3rd IEEE International Conference on Industrial Informatics (INDIN) Perth, Australia 10-12 August 2005
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The advances in information and communication technologies coupled with increased knowledge about genes and proteins have opened new perspectives for study of protein complexes. There is a growing need to integrate the knowledge about various protein complexes for effective disease prevention mechanisms, individualized medicines and treatments and other accepts of healthcare. In this paper we propose a protein ontology that handles the following computational challenges in the area proteomics and systems biology in general: (1) it provides more accurate interpretations and associations as conclusions are based on data and semantics. (2) It makes it possible to study relationships among proteins, protein folding, behaviour of protein under various environments, and most importantly cellular function of protein. This protein ontology is a unified terminology description integrating various protein database schemas and provides a easier way to predict and understand proteins.
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Dillon, Tharam S.; Sidhu, Amandeep; Chang, Elizabeth (2005)In this paper, we proposed a Protein Ontology to integrate protein data and information from various Protein Data Sources. Protein Ontology provides the technical and scientific infrastructure and knowledge to allow ...
Chang, Elizabeth; Sidhu, Amandeep; Sidhu, B.; Dillon, Tharam S. (2005)The rapid generation of accessible protein data sources has generated confusion over protein data representation. The protein ontology project seeks to provide a set of structured vocabularies for protein domains that can ...
Hussain, Farookh Khadeer; Sidhu, Amandeep; Dillon, Tharam S.; Chang, Elizabeth (2006)Biomedical Ontologies are huge. It is not possible for any one person to manage and engineer a complete ontology. They would need the help of Research Assistants and other people to develop and maintain the ontology. In ...