Pharmacokinetics of dihydroartemisinin in a murine malaria model
| dc.contributor.author | Batty, Kevin | |
| dc.contributor.author | Gibbons, Peter | |
| dc.contributor.author | Davis, Timothy | |
| dc.contributor.author | Ilett, K. | |
| dc.date.accessioned | 2017-01-30T13:02:18Z | |
| dc.date.available | 2017-01-30T13:02:18Z | |
| dc.date.created | 2009-03-05T00:56:17Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Batty, Kevin T. and Gibbons, Peter L. and Davis, Timothy M. E. and Ilett, Kenneth F. 2008. Pharmacokinetics of dihydroartemisinin in a murine malaria model. American Journal of Tropical Medicine and Hygiene 78 (4): pp. 641-642. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/27968 | |
| dc.description.abstract |
Pharmacokinetic properties of dihydroartemisinin (DHA) were determined in mice given 100 mg/kg intraperitoneal DHA. Half-life, CL/F, and V/F were 25 min, 61.3 L/hr/kg, and 36.3 L/kg in malaria-infected mice and 19 min, 50.9 L/hr/kg, and 23.0 L/kg in controls. These data are valuable for pharmacokinetic–pharmacodynamic evaluations of DHA in murine models. | |
| dc.publisher | The American Society of Tropical Medicine and Hygiene | |
| dc.title | Pharmacokinetics of dihydroartemisinin in a murine malaria model | |
| dc.type | Journal Article | |
| dcterms.source.volume | 78 | |
| dcterms.source.number | 4 | |
| dcterms.source.startPage | 641 | |
| dcterms.source.endPage | 642 | |
| dcterms.source.issn | 00029637 | |
| dcterms.source.title | American Journal of Tropical Medicine and Hygiene | |
| curtin.accessStatus | Fulltext not available | |
| curtin.faculty | Faculty of Health Sciences | |
| curtin.faculty | School of Pharmacy |