Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Atherosclerosis and Atheroma Plaque Rupture: Normal Anatomy of Vasa Vasorum and Their Role Associated with Atherosclerosis

    197518_110180_285058.pdf (2.114Mb)
    Access Status
    Open access
    Authors
    Sun, Zhonghua
    Date
    2014
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Sun, Zhonghua. 2014. Atherosclerosis and Atheroma Plaque Rupture: Normal Anatomy of Vasa Vasorum and Their Role Associated with Atherosclerosis. The Scientific World Journal. Article ID 285058 (6 pp.).
    Source Title
    The Scientific World Journal
    DOI
    10.1155/2014/285058
    ISSN
    1537-744X
    Remarks

    This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ Please refer to the licence to obtain terms for any further reuse or distribution of this work.

    URI
    http://hdl.handle.net/20.500.11937/28998
    Collection
    • Curtin Research Publications
    Abstract

    Atherosclerosis is primarily a degenerative disorder related to aging with a chronic inflammatory component. There are differences in expression among different vascular beds, inflicting a range of vascular diseases. The majority of studies focus on the inner and medial vascular layers, which are affected at the development of atherosclerosis. Recent evidence shows that the outer layer of blood vessels, composed of the adventitial layer and the vasa vasorum, not only plays a significant role in maintaining vessel integrity, but also reacts to atheroma. What is not clear is the extent of contribution of the outer layer to the process of atherosclerosis. Is it involved in the initiation, progression, and clinical expression of atheroma? Is the inflammation associated with atheroma limited to being merely reactive or is there a proactive element? This paper provides an overview of the normal anatomy of vasa vasorum and potential mechanism of plaque formation due to vascular injury (vasa vasorum) and microhemorrhage.

    Related items

    Showing items related by title, author, creator and subject.

    • Effect of Tie-2 conditional deletion of BDNF on atherosclerosis in the ApoE null mutant mouse
      Norata, Giuseppe; Venu, V.; Callegari, E.; Paloschi, V.; Catapano, A. (2012)
      The reduced expression (haplodeficiency) of the main brain derived neurotrophic factor receptor, namely TrkB is associated with reduced atherosclerosis, smooth muscle cells accumulation and collagen content in the lesion. ...
    • Disease trends over time and CD4+CCR5+ T-cells expansion predict carotid atherosclerosis development in patients with systemic lupus erythematosus
      Baragetti, A.; Ramirez, G.; Magnoni, M.; Garlaschelli, K.; Grigore, L.; Berteotti, M.; Scotti, I.; Bozzolo, E.; Berti, A.; Camici, P.; Catapano, A.; Manfredi, A.; Ammirati, E.; Norata, Giuseppe (2017)
      Background and Aim: Patients with Systemic Lupus Erythematosus (SLE) present increased cardiovascular mortality compared to the general population. Few studies have assessed the long-term development and progression of ...
    • Obesity, arterial function and arterial structure - a systematic review and meta-analysis
      Ne, J.; Cai, T.; Celermajer, D.; Caterson, I.; Gill, T.; Lee, Crystal; Skilton, M. (2017)
      Objective: Obesity is an established risk factor for cardiovascular disease. The mechanisms by which obesity affects cardiovascular risk have not been fully elucidated. This paper reports a comprehensive systematic review ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.