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    Lycopene and prostate cancer: emerging evidence

    Access Status
    Fulltext not available
    Authors
    Fraser, Michelle
    Lee, Andy
    Binns, Colin
    Date
    2005
    Type
    Journal Article
    
    Metadata
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    Citation
    Fraser, Michelle and Lee, Andy and Binns, Colin. 2005. Lycopene and prostate cancer: emerging evidence. Expert Review of Anticancer Therapy 5: 847-854.
    Source Title
    Expert Review of Anticancer Therapy
    DOI
    10.1586/14737140.5.5.847
    Faculty
    School of Public Health
    Division of Health Sciences
    URI
    http://hdl.handle.net/20.500.11937/3039
    Collection
    • Curtin Research Publications
    Abstract

    Prostate cancer has the third highest incidence of all cancers in men worldwide and is the most common neoplasm diagnosed among men beyond middle age in many developed countries. Mounting evidence surrounding the consumption of tomato products has shown promise for the prevention of prostate cancer. This protective effect has more recently been linked to lycopene, the most abundant carotenoid in tomatoes. Lycopene is a natural pigment that gives the red color to many foods. In Western countries, 85% of dietary lycopene can be attributed to the consumption of tomato-based products. This article reviews emerging evidence from epidemiologic studies for the role of lycopene in prostate cancer prevention. The majority of evidence currently comes from observational studies, but recent human clinical trials and animal studies have provided additional support. Growing evidence on the biologic mechanisms of lycopene in prostate cancer prevention also confirm the epidemiologic findings.

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