Age-specific influence of wheezing phenotypes on pre-adolescent and adolescent health-related quality of life
MetadataShow full item record
© 2014 John Wiley & Sons A/S. Introduction: Asthma is associated with diminished health-related quality of life (HRQoL). Particularly in adolescence, asthma may be under-diagnosed and undertreated or poorly managed. Therefore, we aimed to determine the association between childhood wheezing phenotypes rather than asthma and adolescent HRQoL in children aged 10-17 yr. Methods: We analyzed the data from two prospective population-based cohort studies (n = 604 and n = 1804) conducted in southern Germany with baseline assessments in 2000 and 2006 and follow-ups at frequent intervals. Parent-reported wheeze was categorized into never, early transient, persistent, and late-onset wheeze. We assessed child-reported HRQoL in seven scales using the validated KINDL-R. Multivariate linear regression models were computed. Results: Participants with late-onset wheeze had significantly lower values in all HRQoL scales, but physical well-being compared to never wheezers. Early transient wheeze was negatively associated with three HRQoL scales only (family, school, and total). These effects were confined to the oldest age group (=13.5 yr) in one study. Persistent wheeze was not associated with HRQoL. Conclusions: In teenagers, late-onset wheezers seem to be particularly vulnerable for impairments in psychosocial aspects of health-related quality of life.
Showing items related by title, author, creator and subject.
Associations of objectively assessed physical activity and sedentary time with health-related quality of life among lung cancer survivors: A quantile regression approachD'Silva, A.; Gardiner, P.; Boyle, Terry; Bebb, D.; Johnson, S.; Vallance, J. (2018)Â© 2018 Elsevier B.V. Objectives: No studies have examined objectively assessed physical activity, sedentary time, and patient-reported outcomes among lung cancer survivors. The objective of this study was to determine ...
Health-related quality of life and pelvic floor dysfunction in advanced-stage ovarian cancer survivors: associations with objective activity behaviors and physiological characteristicsSchofield, C.; Newton, R.; Cohen, P.; Galvão, D.; McVeigh, Joanne; Mohan, G.; Tan, J.; Salfinger, S.; Straker, Leon; Peddle-McIntyre, C. (2018)© 2018 Springer-Verlag GmbH Germany, part of Springer Nature Purpose: Little is known about the relationship between health-related quality of life (HRQoL), pelvic floor dysfunction (PFD), and modifiable lifestyle and ...
Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivorsVan Roekel, E.; Winkler, E.; Bours, M.; Lynch, B.; Willems, P.; Meijer, K.; Kant, I.; Beets, G.; Sanduleanu, S.; Healy, Genevieve; Weijenberg, M. (2016)Sedentary behavior (sitting/lying at low energy expenditure while awake) is emerging as an important risk factor that may compromise the health-related quality of life (HRQoL) of colorectal cancer (CRC) survivors. We ...