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    Coronary CT angiography: Beyond morphological stenosis analysis

    195937_104764_World_J_Cardiol_2013-2.pdf (2.854Mb)
    Access Status
    Open access
    Authors
    Sun, Zhonghua
    Date
    2013
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Sun, Zhonghua. 2013. Coronary CT angiography: Beyond morphological stenosis analysis. World Journal of Cardiology. 5 (12): pp. 444-452.
    Source Title
    World Journal of Cardiology
    DOI
    10.4330/wjc.v5.i12.444
    ISSN
    1949-8462
    Remarks

    This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/). Please refer to the licence to obtain terms for any further reuse or distribution of this work

    URI
    http://hdl.handle.net/20.500.11937/30813
    Collection
    • Curtin Research Publications
    Abstract

    Rapid technological developments in computed tomography (CT) imaging technique have made coronary CT angiography an attractive imaging tool in the detection of coronary artery disease. Despite visualization of excellent anatomical details of the coronary lumen changes, coronary CT angiography does not provide hemodynamic changes caused by presence of plaques. Computational fluid dynamics (CFD) is a widely used method in the mechanical engineering field to solve complex problems through analysing fluid flow, heat transfer and associated phenomena by using computer simulations. In recent years, CFD is increasingly used in biomedical research due to high performance hardware and software. CFD techniques have been used to study cardiovascular hemodynamics through simulation tools to assist in predicting the behaviour of circulatory blood flow inside the human body. Blood flow plays a key role in the localization and progression of coronary artery disease. CFD simulation based on 3D luminal reconstructions can be used to analyse the local flow fields and flow profiling due to changes of vascular geometry, thus, identifying risk factors for development of coronary artery disease. The purpose of this article is to provide an overview of the coronary CT-derived CFD applications in coronary artery disease.

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