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    Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors

    Access Status
    Fulltext not available
    Authors
    Peters, S.
    Glass, D.
    Reid, Alison
    de Klerk, N.
    Armstrong, B.
    Kellie, S.
    Ashton, L.
    Milne, Elizabeth
    Fritschi, Lin
    Date
    2013
    Type
    Journal Article
    
    Metadata
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    Citation
    Peters, S. and Glass, D. and Reid, A. and de Klerk, N. and Armstrong, B. and Kellie, S. and Ashton, L. et al. 2013. Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors. International Journal of Cancer. 132: pp. 2975-2979.
    Source Title
    International Journal of Cancer
    ISSN
    0020-7136
    Remarks

    Corrected by: Erratum: Parental occupational exposure to engine exhausts and childhood brain tumors, Vol. 135, Issue 7, E7–E8, Article first published online: 15 JUL 2014, doi: 10.1002/ijc.28977

    URI
    http://hdl.handle.net/20.500.11937/31560
    Collection
    • Curtin Research Publications
    Abstract

    Childhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown. Since most CBTs are diagnosed before five years of age, prenatal exposure and early postnatal factors may be involved in their etiology. We investigated the association between CBT and parental occupational exposure to engine exhausts in an Australian population-based case–control study. Parents of 306 cases and 950 controls completed detailed occupational histories. Odds ratios (OR) and 95% confidence intervals (CI) were estimated for both maternal and paternal exposure in keytime periods. Increased risks were observed for maternal exposure to diesel exhaust any time before the child’s birth (OR 2.03, 95% CI 1.09–3.81) and paternal exposure around the time of the child’s conception (OR 1.62, 95% CI 1.12–2.34). No clear associations with other engine exhausts were found. Our results suggest that parental occupational exposure to diesel exhaust may increase the risk of CBT.

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