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dc.contributor.authorWard, Natalie
dc.contributor.authorBondonno, N.
dc.contributor.authorBondonno, C.
dc.contributor.authorHodgson, J.
dc.contributor.authorCroft, K.
dc.date.accessioned2017-01-30T13:39:14Z
dc.date.available2017-01-30T13:39:14Z
dc.date.created2016-01-19T20:00:31Z
dc.date.issued2015
dc.identifier.citationBondonno, N. and Bondonno, C. and Hodgson, J. and Ward, N. and Croft, K. 2015. The Efficacy of Quercetin in Cardiovascular Health. Current Nutrition Reports. 4 (4): pp. 290-303.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/33755
dc.identifier.doi10.1007/s13668-015-0137-3
dc.description.abstract

Cardiovascular disease is a major cause of death worldwide despite the majority of its risk factors being preventable and treatable. The results of numerous epidemiological studies suggest that a diet rich in fruits and vegetables affords protection against CVD, and this may be attributed, in part, to the flavonoid quercetin. The aims of this review are to summarise the current knowledge on the bioavailability and metabolism of quercetin as well as discuss the current evidence behind the potential mechanisms by which quercetin exerts its cardioprotective effects. This review summarises key human studies administering quercetin that have been published to date. Although interesting results have been seen in animal and cell culture studies, in general, these have not been replicated in human trials. Several studies have, however, shown that quercetin can reduce blood pressure in hypertensive patients. The exact mechanisms are yet to be elucidated. Further studies are required to investigate the use of quercetin as a cardioprotective treatment, in particular long-term and dose–response studies.

dc.titleThe Efficacy of Quercetin in Cardiovascular Health
dc.typeJournal Article
dcterms.source.volume4
dcterms.source.startPage290
dcterms.source.endPage303
dcterms.source.titleCurrent Nutrition Reports
curtin.departmentSchool of Biomedical Sciences
curtin.accessStatusFulltext not available


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