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    Age-related changes in short-interval intracortical facilitation and dexterity

    225595_225595.pdf (383.7Kb)
    Access Status
    Open access
    Authors
    Clark, J.
    Loftus, Andrea
    Hammond, G.
    Date
    2011
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Clark, J. and Loftus, A. and Hammond, G. 2011. Age-related changes in short-interval intracortical facilitation and dexterity. NeuroReport. 22 (10): pp. 499-503.
    Source Title
    NeuroReport
    ISSN
    0959-4965
    Remarks

    This is a non-final version of an article published in final form in Clark, J. and Loftus, A. and Hammond, G. 2011. Age-related changes in short-interval intracortical facilitation and dexterity. NeuroReport. 22 (10): pp. 499-503.

    URI
    http://hdl.handle.net/20.500.11937/39178
    Collection
    • Curtin Research Publications
    Abstract

    Functional changes in the primary motor cortex might contribute to the age-related decline infine motor control. We measured short-interval intracortical facilitation (SICF) in an intrinsichand muscle with paired-pulse transcranial magnetic stimulation at interstimulus intervals(ISIs) of 1.5, 2.5, and 4.5 ms in young and old subjects and examined its association withdexterity. We found age-related effects in SICF, with greater facilitation in old than youngsubjects at the 1.5-ms ISI and greater facilitation in young than old subjects at the 2.5-ms ISI.SICF at the 2.5-ms ISI was positively correlated with performance on a task that requiredcoordinated and dextrous use of both hands, suggesting that this measure indicates a capacityfor executing demanding manual tasks.

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