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dc.contributor.authorClark, J.
dc.contributor.authorLoftus, Andrea
dc.contributor.authorHammond, G.
dc.date.accessioned2017-01-30T14:31:20Z
dc.date.available2017-01-30T14:31:20Z
dc.date.created2015-04-23T03:53:25Z
dc.date.issued2011
dc.identifier.citationClark, J. and Loftus, A. and Hammond, G. 2011. Age-related changes in short-interval intracortical facilitation and dexterity. NeuroReport. 22 (10): pp. 499-503.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/39178
dc.description.abstract

Functional changes in the primary motor cortex might contribute to the age-related decline infine motor control. We measured short-interval intracortical facilitation (SICF) in an intrinsichand muscle with paired-pulse transcranial magnetic stimulation at interstimulus intervals(ISIs) of 1.5, 2.5, and 4.5 ms in young and old subjects and examined its association withdexterity. We found age-related effects in SICF, with greater facilitation in old than youngsubjects at the 1.5-ms ISI and greater facilitation in young than old subjects at the 2.5-ms ISI.SICF at the 2.5-ms ISI was positively correlated with performance on a task that requiredcoordinated and dextrous use of both hands, suggesting that this measure indicates a capacityfor executing demanding manual tasks.

dc.publisherLippincott Williams & Wilkins
dc.subjectmanual dexterity
dc.subjectmotor control
dc.subjectTMS
dc.subjectageing
dc.subjectSICF
dc.subjectmotor cortex
dc.subjectaging
dc.titleAge-related changes in short-interval intracortical facilitation and dexterity
dc.typeJournal Article
dcterms.source.volume22
dcterms.source.number10
dcterms.source.startPage499
dcterms.source.endPage503
dcterms.source.issn0959-4965
dcterms.source.titleNeuroReport
curtin.note

This is a non-final version of an article published in final form in Clark, J. and Loftus, A. and Hammond, G. 2011. Age-related changes in short-interval intracortical facilitation and dexterity. NeuroReport. 22 (10): pp. 499-503.

curtin.accessStatusOpen access


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