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dc.contributor.authorSolah, Vicky
dc.contributor.authorBrand-Miller, J.
dc.contributor.authorAtkinson, F.
dc.contributor.authorGahler, R.
dc.contributor.authorKacinik, V.
dc.contributor.authorLyon, M.
dc.contributor.authorWood, S.
dc.date.accessioned2017-01-30T14:34:20Z
dc.date.available2017-01-30T14:34:20Z
dc.date.created2014-05-15T20:00:18Z
dc.date.issued2014
dc.identifier.citationSolah, V. and Brand-Miller, J. and Atkinson, F. and Gahler, R. and Kacinik, V. and Lyon, M. and Wood, S. 2014. Dose–response effect of a novel functional fibre, PolyGlycopleX®, PGX®, on satiety. Appetite. 77: pp. 74-78.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/39486
dc.identifier.doi10.1016/j.appet.2014.02.021
dc.description.abstract

The objective of this research was to determine the dose–response effects of a palatable, viscous and gel forming fibre, PolyGlycopleX® (PGX®), [(a-D-glucurono-a–manno-ß-D-manno-ß-D-gluco), (a-Lgulurono-ß-D mannurono), (ß-D-gluco-ß-D-mannan)] on satiety, and to gain insight into the underlying mechanisms that lead to appetite inhibition. Healthy subjects (n = 10), aged between 20.3 and 29.2 years, consumed PGX®, in granular form at 2.5, 5.0 and 7.5 g, and a 5g inulin control, with a standard breakfast. The PGX® doses of 2.5 and 7.5 g mixed with water at the start of breakfast increased satiety (iAUC of 140.0 and 157.7,P = 0.025 and 0.001, respectively) compared to the control. The most effective dose (7.5g) was palatable and corresponded to a 34% increase in fullness, measured using a visual analogue scale and incremental area under the curve, and resulted in a delayed postprandial glycaemic response when compared with the control.

dc.publisherElsevier BV
dc.subjectsatiety
dc.subjectfibre
dc.subjectdose
dc.titleDose–response effect of a novel functional fibre, PolyGlycopleX®, PGX®, on satiety
dc.typeJournal Article
dcterms.source.volume77
dcterms.source.startPage72
dcterms.source.endPage76
dcterms.source.issn0195-6663
dcterms.source.titleAppetite
curtin.department
curtin.accessStatusOpen access via publisher


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