Protein ontology development using OWL
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To efficiently represent the protein annotation framework and to integrate all the existing data representations into a standardized protein data specification for the bioinformatics community, the protein ontology need to be represented in a format that not enforce semantic constraints on protein data, but can also facilitate reasoning tasks on protein data using semantic query algebra. This motivates the representation of Protein Ontology (PO) Model in Web Ontology Language (OWL). In this paper we briefly discuss the usage of OWL in achieving the objectives of Protein Ontology Project. We provide a brief overview of Protein Ontology (PO) to start with. In the later sections discuss why OWL was an ideal choice for PO Development.
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Chang, Elizabeth; Sidhu, Amandeep; Dillon, Tharam S. (2005)In this paper, we proposed a Protein Ontology to integrate protein data and information from various Protein Data Sources. Protein Ontology provides the technical and scientific infrastructure and knowledge to allow ...
Chang, Elizabeth; Sidhu, Amandeep; Sidhu, B.; Dillon, Tharam S. (2005)The rapid generation of accessible protein data sources has generated confusion over protein data representation. The protein ontology project seeks to provide a set of structured vocabularies for protein domains that can ...
Sidhu, Amandeep; Dillon, Tharam S.; Chang, Elizabeth (2007)These Huge amounts of Protein Structure Data make it difficult to create explanatory and predictive models that are consistent with huge volume of data. Difficulty increase when large variety of heterogeneous approaches ...