Living well with diabetes: 24-month outcomes from a randomized trial of telephone-delivered weight loss and physical activity intervention to improve glycemic control
MetadataShow full item record
OBJECTIVE: To evaluate the effectiveness of a telephone-delivered behavioral weight loss and physical activity intervention targeting Australian primary care patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: Pragmatic randomized controlled trial of telephone counseling (n = 151) versus usual care (n = 151). Reported here are 18-month (end-of-intervention) and 24-month (maintenance) primary outcomes of weight, moderate-to-vigorous- intensity physical activity (MVPA; via accelerometer), and HbA<inf>1c</inf> level. Secondary outcomes include dietary energy intake and diet quality, waist circumference, lipid levels, and blood pressure. Data were analyzed via adjusted linear mixed models with multiple imputation of missing data. RESULTS: Relative to usual-care participants, telephone counseling participants achieved modest, but significant, improvementsin weight loss (relative rate [RR] 21.42% of baseline body weight [95% CI 22.54 to 20.30% of baseline body weight]), MVPA (RR 1.42 [95% CI 1.06-1.90]), diet quality (2.72 [95% CI 0.55-4.89]), and waist circumference (21.84 cm [95% CI 23.16 to 20.51 cm]), but not in HbA<inf>1c</inf> level (RR 0.99 [95% CI 0.96-1.02]), or other cardio-metabolic markers. None of the outcomes showed a significant change/deterioration over the maintenance period. However, only the intervention effect for MVPA remained statistically significant at 24 months. CONCLUSIONS: The modest improvements in weight loss and behavior change, but the lack of changes in cardio-metabolic markers, may limit the utility, scalability, and sustainability of such an approach. © 2014 by the American Diabetes Association.
Showing items related by title, author, creator and subject.
Living well after breast cancer randomized controlled trial protocol: evaluating a telephone-delivered weight loss intervention versus usual care in women following treatment for breast cancerReeves, M.; Terranova, C.; Erickson, J.; Job, J.; Brookes, D.; McCarthy, N.; Hickman, I.; Lawler, S.; Fjeldsoe, B.; Healy, Genevieve; Winkler, E.; Janda, M.; Veerman, J.; Ware, R.; Prins, J.; Vos, T.; Demark-Wahnefried, W.; Eakin, E. (2016)BACKGROUND: Obesity, physical inactivity and poor diet quality have been associated with increased risk of breast cancer-specific and all-cause mortality as well as treatment-related side-effects in breast cancer survivors. ...
Living well with diabetes: A randomized controlled trial of a telephone-delivered intervention for maintenance of weight loss, physical activity and glycaemic control in adults with type 2 diabetesEakin, E.; Reeves, M.; Marshall, A.; Dunstan, D.; Graves, N.; Healy, Genevieve; Bleier, J.; Barnett, A.; O'Moore-Sullivan, T.; Russell, A.; Wilkie, K. (2010)Background. By 2025, it is estimated that approximately 1.8 million Australian adults (approximately 8.4% of the adult population) will have diabetes, with the majority having type 2 diabetes. Weight management via improved ...
Six-month outcomes from living well with diabetes: A randomized trial of a telephone-delivered weight loss and physical activity intervention to improve glycemic controlEakin, E.; Reeves, M.; Winkler, E.; Healy, Genevieve; Dunstan, D.; Owen, N.; Marshal, A.; Wilkie, K. (2013)Background: Intensive lifestyle intervention trials in type 2 diabetes contribute evidence on what can be achieved under optimal conditions, but are less informative for translation in applied settings. Purpose: Living ...