Living well with diabetes: 24-month outcomes from a randomized trial of telephone-delivered weight loss and physical activity intervention to improve glycemic control
|dc.identifier.citation||Eakin, E. and Winkler, E. and Dunstan, D. and Healy, G. and Owen, N. and Marshall, A. and Graves, N. et al. 2014. Living well with diabetes: 24-month outcomes from a randomized trial of telephone-delivered weight loss and physical activity intervention to improve glycemic control. Diabetes Care. 37 (8): pp. 2177-2185.|
OBJECTIVE: To evaluate the effectiveness of a telephone-delivered behavioral weight loss and physical activity intervention targeting Australian primary care patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: Pragmatic randomized controlled trial of telephone counseling (n = 151) versus usual care (n = 151). Reported here are 18-month (end-of-intervention) and 24-month (maintenance) primary outcomes of weight, moderate-to-vigorous- intensity physical activity (MVPA; via accelerometer), and HbA<inf>1c</inf> level. Secondary outcomes include dietary energy intake and diet quality, waist circumference, lipid levels, and blood pressure. Data were analyzed via adjusted linear mixed models with multiple imputation of missing data. RESULTS: Relative to usual-care participants, telephone counseling participants achieved modest, but significant, improvementsin weight loss (relative rate [RR] 21.42% of baseline body weight [95% CI 22.54 to 20.30% of baseline body weight]), MVPA (RR 1.42 [95% CI 1.06-1.90]), diet quality (2.72 [95% CI 0.55-4.89]), and waist circumference (21.84 cm [95% CI 23.16 to 20.51 cm]), but not in HbA<inf>1c</inf> level (RR 0.99 [95% CI 0.96-1.02]), or other cardio-metabolic markers. None of the outcomes showed a significant change/deterioration over the maintenance period. However, only the intervention effect for MVPA remained statistically significant at 24 months. CONCLUSIONS: The modest improvements in weight loss and behavior change, but the lack of changes in cardio-metabolic markers, may limit the utility, scalability, and sustainability of such an approach. © 2014 by the American Diabetes Association.
|dc.publisher||American Diabetes Association Inc.|
|dc.title||Living well with diabetes: 24-month outcomes from a randomized trial of telephone-delivered weight loss and physical activity intervention to improve glycemic control|
|curtin.department||School of Physiotherapy and Exercise Science|
|curtin.accessStatus||Open access via publisher|
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