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    Screening for Down syndrome in the second trimester of pregnancy.

    Access Status
    Fulltext not available
    Authors
    O'Leary, Peter
    Maxwell, S.
    Sinosich, M.
    DeVoss, K.
    Fletcher, J.
    Ranieri, E.
    Metz, M.
    Date
    2016
    Type
    Journal Article
    
    Metadata
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    Citation
    O'Leary, P. and Maxwell, S. and Sinosich, M. and DeVoss, K. and Fletcher, J. and Ranieri, E. and Metz, M. 2016. Screening for Down syndrome in the second trimester of pregnancy. Australian and New Zealand Journal of Obstetrics and Gymaecology. 56 (1): pp. 19-21.
    Source Title
    Aust N Z J Obstet Gynaecol
    DOI
    10.1111/ajo.12411
    School
    Health Sciences Research and Graduate Studies
    URI
    http://hdl.handle.net/20.500.11937/4130
    Collection
    • Curtin Research Publications
    Abstract

    Antenatal screening for fetal anomalies has provided women and their partners with information to make reproductive choices based on the risk of serious chromosomal or structural defects since the 1990s. Alternative tests include first-trimester screening (combined ultrasound and maternal serum markers), second-trimester maternal serum markers and noninvasive cell-free DNA testing. The recent recommendations by the Royal Australian and New Zealand College of Obstetrics and Gynaecology and the Human Genetics Society of Australasia against second-trimester triple testing are based on unsound performance criteria, raise several contestable issues around access and equity and challenge the principles of governments providing affordable options.

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