Alzheimer's amyloid-ß rescues yeast from hydroxide toxicity
| dc.contributor.author | Dubey, A. | |
| dc.contributor.author | Bharadwaj, Prashant | |
| dc.contributor.author | Varghese, J. | |
| dc.contributor.author | MacReadie, I. | |
| dc.date.accessioned | 2017-01-30T14:59:58Z | |
| dc.date.available | 2017-01-30T14:59:58Z | |
| dc.date.created | 2016-09-12T08:36:25Z | |
| dc.date.issued | 2009 | |
| dc.identifier.citation | Dubey, A. and Bharadwaj, P. and Varghese, J. and MacReadie, I. 2009. Alzheimer's amyloid-ß rescues yeast from hydroxide toxicity. Journal of Alzheimer's Disease. 18 (1): pp. 31-33. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/42488 | |
| dc.identifier.doi | 10.3233/JAD-2009-1121 | |
| dc.description.abstract |
Amyloid-ß (Aß-{42}), which is known to be toxic to neuronal cells, protects yeast cells from severe sodium hydroxide toxicity. More than 85% cell death was caused by treatment with 1 mM NaOH and approximately 95% was observed at a 2 mM concentration. However, greater than 55% cells survived the treatment in the presence of Aß-{42}. A strong protective effect of the peptide was also evident from the differential staining of the treated culture with propidium iodide. © 2009 - IOS Press and the authors. All rights reserved. | |
| dc.publisher | IOS Press | |
| dc.title | Alzheimer's amyloid-ß rescues yeast from hydroxide toxicity | |
| dc.type | Journal Article | |
| dcterms.source.volume | 18 | |
| dcterms.source.number | 1 | |
| dcterms.source.startPage | 31 | |
| dcterms.source.endPage | 33 | |
| dcterms.source.issn | 1387-2877 | |
| dcterms.source.title | Journal of Alzheimer's Disease | |
| curtin.department | School of Biomedical Sciences | |
| curtin.accessStatus | Fulltext not available |
Files in this item
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||