Show simple item record

dc.contributor.authorBoyle, T.
dc.contributor.authorHeyworth, J.
dc.contributor.authorBull, F.
dc.contributor.authorMcKerracher, S.
dc.contributor.authorPlatell, C.
dc.contributor.authorFritschi, Lin
dc.date.accessioned2017-01-30T15:10:58Z
dc.date.available2017-01-30T15:10:58Z
dc.date.created2015-03-03T03:50:53Z
dc.date.issued2012
dc.date.submitted2015-03-03
dc.identifier.citationBoyle, T. and Heyworth, J. and Bull, F. and McKerracher, S. and Platell, C. and Fritschi, L. 2012. Timing and intensity of recreational physical activity and the risk of subsite-specific colorectal cancer. Cancer Causes and Control. 22 (12): pp. 1647-1658.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/43933
dc.identifier.doi10.1007/s10552-011-9841-5
dc.description.abstract

Purpose: Although there is convincing evidence that physical activity reduces colon cancer risk, there are important questions that remain unanswered about the association. These include the timing and intensity of activity required to optimally reduce risk, and whether physical activity has a different effect on cancers at different sites within the colon. We conducted a case–control study to investigate these issues. Methods: A case–control study of colorectal cancer was conducted in Western Australia in 2005–2007. Data were collected on various risk factors. The estimated effects of recreational physical activity on the risk of cancers of the distal colon, proximal colon, and rectum were analyzed using multinomial logistic regression. This analysis included 870 cases and 996 controls. Results: The risk of distal colon cancer was reduced by performing a high level of vigorous-intensity activity between the ages 19 and 34 years (women), 35 and 50 years (men), after the age of 51 years (men and women), and consistently over the adult lifetime (men and women). The risk of rectal cancer was reduced by performing a high level of vigorous activity between the ages 35 and 50 years (men), and consistently over the adult lifetime (men). Proximal colon cancer risk was not associated with physical activity in any of the age periods or over the adult lifetime. Moderate intensity activity did not reduce the risk of colorectal cancer. Conclusion: Physical activity may have a greater effect on the risk of distal colon cancer than proximal colon cancer. Vigorous physical activity is required to reduce colorectal cancer risk.

dc.publisherKluwer Academic Publishers
dc.titleTiming and intensity of recreational physical activity and the risk of subsite-specific colorectal cancer
dc.typeJournal Article
dcterms.dateSubmitted2015-03-03
dcterms.source.volume22
dcterms.source.number12
dcterms.source.startPage1647
dcterms.source.endPage1658
dcterms.source.issn09575243
dcterms.source.titleCancer Causes and Control
curtin.digitool.pid213949
curtin.pubStatusPublished
curtin.refereedTRUE
curtin.identifier.scriptidPUB-HEA-SPH-MT-86309
curtin.accessStatusFulltext not available


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record