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    A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation

    Access Status
    Fulltext not available
    Authors
    Lim, Felicia Phei Lin
    Luna, Giuseppe
    Dolzhenko, Anton
    Date
    2014
    Type
    Journal Article
    
    Metadata
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    Citation
    Lim, F.P.L. and Luna, G. and Dolzhenko, A. 2014. A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation. Tetrahedron Letters. 55 (37): pp. 5159-5163.
    Source Title
    Tetrahedron Letters
    DOI
    10.1016/j.tetlet.2014.07.105
    ISSN
    0040-4039
    School
    School of Pharmacy
    URI
    http://hdl.handle.net/20.500.11937/44673
    Collection
    • Curtin Research Publications
    Abstract

    A new, practical, three-component method for the synthesis of 5-aza-9-deaza-adenines is developed. Aminopyrazoles react in a one-pot fashion with triethyl orthoformate and cyanamide under microwave irradiation affording 5-aza-9-deaza-adenines in good yields and high purity. The main advantages of this method are the operational simplicity, accessibility and high efficiency

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