A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
| dc.contributor.author | Lim, Felicia Phei Lin | |
| dc.contributor.author | Luna, Giuseppe | |
| dc.contributor.author | Dolzhenko, Anton | |
| dc.date.accessioned | 2017-01-30T15:15:42Z | |
| dc.date.available | 2017-01-30T15:15:42Z | |
| dc.date.created | 2014-09-04T20:00:22Z | |
| dc.date.issued | 2014 | |
| dc.identifier.citation | Lim, F.P.L. and Luna, G. and Dolzhenko, A. 2014. A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation. Tetrahedron Letters. 55 (37): pp. 5159-5163. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/44673 | |
| dc.identifier.doi | 10.1016/j.tetlet.2014.07.105 | |
| dc.description.abstract |
A new, practical, three-component method for the synthesis of 5-aza-9-deaza-adenines is developed. Aminopyrazoles react in a one-pot fashion with triethyl orthoformate and cyanamide under microwave irradiation affording 5-aza-9-deaza-adenines in good yields and high purity. The main advantages of this method are the operational simplicity, accessibility and high efficiency | |
| dc.publisher | Pergamon | |
| dc.subject | Cyanamide | |
| dc.subject | Multicomponent reaction | |
| dc.subject | Triazine | |
| dc.subject | Pyrazole | |
| dc.subject | Purine analogue | |
| dc.title | A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation | |
| dc.type | Journal Article | |
| dcterms.source.volume | 55 | |
| dcterms.source.startPage | 5159 | |
| dcterms.source.endPage | 5163 | |
| dcterms.source.issn | 0040-4039 | |
| dcterms.source.title | Tetrahedron Letters | |
| curtin.department | School of Pharmacy | |
| curtin.accessStatus | Fulltext not available |