Show simple item record

dc.contributor.authorGordon, A.
dc.contributor.authorMarbach, C.
dc.contributor.authorOakey, J.
dc.contributor.authorEdmunds, G.
dc.contributor.authorCondon, K.
dc.contributor.authorDiviney, Sinead
dc.contributor.authorWilliams, David
dc.contributor.authorBingham, J.
dc.date.accessioned2017-01-30T15:17:04Z
dc.date.available2017-01-30T15:17:04Z
dc.date.created2012-11-01T20:00:24Z
dc.date.issued2012
dc.identifier.citationGordon, Anita and Marbach, Cameron and Oakey, Jane and Edmunds, Glen and Condon, Kelly and Diviney, Sinead and Williams, David and Bingham, John. 2012. Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. Journal of Veterinary Diagnostic Investigation. 24 (2): pp. 431-436.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/44892
dc.identifier.doi10.1177/1040638711433325
dc.description.abstract

A five year old Australian stock horse in Monto, Queensland, developed neurological signs and was euthanized after a six day course of illness. Histological examination of the brain and spinal cord revealed moderate to severe, subacute, non-suppurative encephalomyelitis. Sections of spinal cord stained positively in immunohistochemistry with a flavivirus-specific monoclonal antibody. Reverse transcription-polymerase chain reaction assay targeting the envelope gene of flavivirus yielded positive results from brain, spinal cord, cerebrospinal fluid and facial nerve. A flavivirus was isolated from the cerebrum and spinal cord. Nucleotide sequences obtained from amplicons from both tissues and virus isolated in cell culture were compared with those in GenBank, and had 96-98% identity with Murray Valley encephalitis virus. The partial envelope gene sequence of the viral isolate clustered into Genotype 1, and was most closely related to a previous Queensland isolate. This is the first confirmed case of naturally-occurring equine encephalitis attributable to Murray Valley encephalitis virus infection.

dc.publisherSAGE Publications
dc.subjectMurray Valley encephalitis virus
dc.subjectflavivirus
dc.subjecthorses
dc.subjectEncephalitis
dc.titleConfirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse
dc.typeJournal Article
dcterms.source.volume24
dcterms.source.number2
dcterms.source.startPage431
dcterms.source.endPage436
dcterms.source.issn10406387
dcterms.source.titleJournal of Veterinary Diagnostic Investigation
curtin.note

The final, definitive version of this paper has been published in Journal of Veterinary Diagnostic Investigation, 24 (2), March 2012 by SAGE Publications Ltd, All rights reserved. © Anita N. Gordon

curtin.department
curtin.accessStatusOpen access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record