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dc.contributor.authorCoombe, Deirdre
dc.contributor.authorDye, Danielle
dc.contributor.editorPreedy, Victor R.
dc.date.accessioned2017-01-30T15:27:32Z
dc.date.available2017-01-30T15:27:32Z
dc.date.created2011-03-15T20:01:43Z
dc.date.issued2010
dc.identifier.citationCoombe, Deirdre R. and Dye, Danielle E. 2010. Feature, Structure and Classification of Adhesion Molecules: An Overview, in Preedy, V.R. (ed), Adhesion Molecules. pp. 1-19. United States of America: Taylor & Francis.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/46473
dc.description.abstract

Cell adhesion molecules allow cells to communicate with each other and with their environment. The interactions between cell adhesion receptors and their ligands orchestrate the assembly of cells into tissues, organs and systems, and lead to the formation of multicellular organisms. Numerous different adhesive events, which may be synergistic or antagonistic, are required for organizing a tissue or a cell behavior. It is the balance between these events that determines the structure of a tissue, or whether cells stay in tight association with other cells or migrate around the body.There are four main families of cell adhesion receptors: the immunoglobulin superfamily, integrins, cadherins and selectins. The cadherins mediate strong cell-cell adhesion and play a fundamental role in morphogenesis and development, while integrins are critical to cell-matrix interactions and cell migration through the extracellular matrix. Immunoglobulin superfamily members contribute to and modulate cell-cell interactions. These three large families contribute to adhesive interactions between many cell types in different tissues. The selectins have three members and they perform a very specific role critical for leukocyte migration from the vasculature.

dc.publisherScience Publishers
dc.subjectCadherin
dc.subjectIg-superfamily member
dc.subjectAdhesion molecules
dc.subjectSelectin
dc.subjectIntegrin
dc.titleFeature, Structure and Classification of Adhesion Molecules: An Overview
dc.typeBook Chapter
dcterms.source.startPage1
dcterms.source.endPage19
dcterms.source.titleAdhesion Molecules
dcterms.source.isbn978-1-57808-671-9
dcterms.source.placeEnfield, New Hampshire, USA
dcterms.source.chapter31
curtin.note

Copyright © 2010 from Adhesion Molecules by Preedy, V.R. Reproduced by permission of Taylor and Francis Group, LLC, a division of Informa plc.

curtin.departmentMolecular Immunology / Bio Sciences
curtin.accessStatusFulltext not available


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