Show simple item record

dc.contributor.authorSiafarikas, A.
dc.contributor.authorJohnston, R.
dc.contributor.authorBulsara, M.
dc.contributor.authorO'Leary, Peter
dc.contributor.authorJones, T.
dc.contributor.authorDavis, E.
dc.identifier.citationSiafarikas, A. and Johnston, R. and Bulsara, M. and O'Leary, P. and Jones, T. and Davis, E. 2012. Early Loss of the Glucagon Response to Hypoglycemia in Adolescents with Type 1 Diabetes. Diabetes Care. 35: pp. 1757-1762.

Objective: To assess the glucagon response to hypoglycemia and identify influencing factors in patients with type 1 diabetes compared with nondiabetic control subjects.Research design and methods - Hyperinsulinemic hypoglycemic clamp studies were performed in all participants. The glucagon response to both hypoglycemia and arginine was measured, as well as epinephrine, cortisol, and growth hormone responses to hypoglycemia. Residual ß-cell function was assessed using fasting and stimulated C-peptide.Conclusions - The glucagon response to hypoglycemia in adolescents with type 1 diabetes is influenced by the duration of diabetes and can be lost early in the course of the disesase.

dc.publisherAmerican Diabetes Association
dc.subjectglucagon response
dc.subjecttype 1 diabetes
dc.titleEarly Loss of the Glucagon Response to Hypoglycemia in Adolescents with Type 1 Diabetes
dc.typeJournal Article
dcterms.source.titleDiabetes Care
curtin.departmentCentre for Population Health Research
curtin.accessStatusOpen access

Files in this item


This item appears in the following Collection(s)

Show simple item record
Except where otherwise noted, this item's license is described as