Show simple item record

dc.contributor.authorBrenner, H.
dc.contributor.authorAltenhofen, L.
dc.contributor.authorKatalinic, A.
dc.contributor.authorLansdorp_Vogelaar, Iris
dc.contributor.authorHoffmeister, M.
dc.date.accessioned2017-03-15T22:17:12Z
dc.date.available2017-03-15T22:17:12Z
dc.date.created2017-02-26T19:31:40Z
dc.date.issued2011
dc.identifier.citationBrenner, H. and Altenhofen, L. and Katalinic, A. and Lansdorp_Vogelaar, I. and Hoffmeister, M. 2011. Sojourn time of preclinical colorectal cancer by sex and age: Estimates from the german national screening colonoscopy database. American Journal of Epidemiology. 174 (10): pp. 1140-1146.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/50057
dc.identifier.doi10.1093/aje/kwr188
dc.description.abstract

The sojourn time of preclinical colorectal cancer is a critical parameter in modeling effectiveness and cost-effectiveness of colorectal cancer screening. For ethical reasons, it cannot be observed directly, and available estimates are based mostly on relatively small historic data sets that do not include differentiation by age and sex. The authors derived sex-and age-specific estimates (age groups: 55-59, 60-64, 65-69, 70-74, 75-79, and =80 years) of mean sojourn time, combining data from the German national screening colonoscopy registry (based on 1.88 million records) and data from population-based cancer registries (population base: 37.9 million people) for the years 2003-2006. Estimates of mean sojourn time were similar for both sexes and all age groups and ranged from 4.5 years (95% confidence interval: 4.1, 4.8) to 5.8 years (95% confidence interval: 5.3, 6.3) for the subgroups assessed. Sensitivity analyses indicated that mean sojourn time might be approximately 1.5 years longer if colorectal cancer prevalence in nonparticipants of screening colonoscopy is 20% lower than prevalence in participants or 1 year shorter if it exceeds the prevalence in participants by 20%. This study provides, for the first time, precise estimates of sojourn time by age and sex, and it suggests that sojourn times are remarkably consistent across age groups and in both sexes. © 2011 The Author.

dc.publisherOxford University Press
dc.titleSojourn time of preclinical colorectal cancer by sex and age: Estimates from the german national screening colonoscopy database
dc.typeJournal Article
dcterms.source.volume174
dcterms.source.number10
dcterms.source.startPage1140
dcterms.source.endPage1146
dcterms.source.issn0002-9262
dcterms.source.titleAmerican Journal of Epidemiology
curtin.accessStatusOpen access via publisher


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record