Show simple item record

dc.contributor.authorUllmann, J.
dc.contributor.authorWatson, Charles
dc.contributor.authorJanke, A.
dc.contributor.authorKurniawan, N.
dc.contributor.authorReutens, D.
dc.date.accessioned2017-01-30T10:43:38Z
dc.date.available2017-01-30T10:43:38Z
dc.date.created2014-04-15T20:01:00Z
dc.date.issued2013
dc.identifier.citationUllmann, Jeremy F.P. and Watson, Charles and Janke, Andrew L. and Kurniawan, Nyoman D. and Reutens, David C. 2013. A segmentation protocol and MRI atlas of the C57BL/6J mouse neocortex. NeuroImage. 78: pp. 196-203.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/5061
dc.identifier.doi10.1016/j.neuroimage.2013.04.008
dc.description.abstract

The neocortex is the largest component of the mammalian cerebral cortex. It integrates sensory inputs with experiences and memory to produce sophisticated responses to an organism's internal and external environment. While areal patterning of the mouse neocortex has been mapped using histological techniques, the neocortex has not been comprehensively segmented in magnetic resonance images. This study presents a method for systematic segmentation of the C57BL/6J mouse neocortex. We created a minimum deformation atlas, which was hierarchically segmented into 74 neocortical and cortical-related regions, making it the most detailed atlas of the mouse neocortex currently available. In addition, we provide mean volumes and relative intensities for each structure as well as a nomenclature comparison between the two most cited histological atlases of the mouse brain. This MR atlas is available for download, and it should enable researchers to perform automated segmentation in genetic models of cortical disorders.

dc.publisherAcademic Press
dc.subjectCortex
dc.subjectMagnetic resonance imaging
dc.subjectSegmentation
dc.subjectIsocortex
dc.subjectAtlas
dc.titleA segmentation protocol and MRI atlas of the C57BL/6J mouse neocortex
dc.typeJournal Article
dcterms.source.volume78
dcterms.source.startPage196
dcterms.source.endPage203
dcterms.source.issn1053-8119
dcterms.source.titleNeuroImage
curtin.department
curtin.accessStatusFulltext not available


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record