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    Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status

    Access Status
    Fulltext not available
    Authors
    Chai, J.
    Chau, Anson
    Chu, F.
    Chow, T.
    Date
    2014
    Type
    Journal Article
    
    Metadata
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    Citation
    Chai, J. and Chau, A. and Chu, F. and Chow, T. 2014. Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status. International Journal of Oral and Maxillofacial Implants. 29 (3): pp. 667-674.
    Source Title
    International Journal of Oral and Maxillofacial Implants
    ISSN
    0882-2786
    School
    Department of Medical Radiation Sciences
    URI
    http://hdl.handle.net/20.500.11937/50887
    Collection
    • Curtin Research Publications
    Abstract

    PURPOSE: The study evaluated the diagnostic performance of computed tomography (CT) bone density measurements (in Hounsfield units [HU]) in assessing the osteoporotic status of edentulous subjects (21 men, 40 women) scheduled to receive mandibular implant-supported overdentures. MATERIALS AND METHODS: Density (in HU) of 61 left and 61 right mandibular canine sites was measured. Each subject was also subject to body bone mineral density measurements (dual-energy x-ray absorptiometry). Bone density T-score values of total hip, femoral neck, spine (L1 to L4), and total body were assessed. Pearson correlations were conducted between HU of each mandibular bone site and the subject's T-score values. Sensitivity/specificity and receiver operating characteristic curve analyses were used to assess the diagnostic performance of HU in detecting subjects who were, based on each of the four T-scores: (1) "not osteonormal", ie, with a T-score at or below -1.0; or (2) osteoporotic, ie, with a T-score at or below -2.5. RESULTS: HU measurements of mandibular bone sites were found to have modest but significant correlations with each bone density T-score value (total hip, femoral neck, spine, total body). CT mandibular site HU measurement has diagnostic value in detecting a "not osteonormal" condition when total hip, spine, or total body T-scores were used, but not when femoral neck T-score was used. CONCLUSIONS: Based on the limited sample size, optimal HU cutoff values of ~530, ~600, and ~640 HU for total hip, spine, or total body T-scores, respectively, were proposed. CT mandibular site HU measurement had diagnostic value in detecting osteoporosis when spine T-score was used but not when total hip, femoral neck, and total body T-scores were used. An optimal HU cutoff value of ~460 HU for spine T-score was proposed.

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